Active Motif, Inc. is a privately held biotechnology company focused on supplying innovative kits and reagents for epigenetics and nuclear function research.

Commitment to Customers

Commitment to Excellence

Innovation

Accountability

Integrity

Teamwork

The position has dual responsibilities, split between development of new recombinant and polyclonal antibodies and their characterization in value-added applications (75%) and performing activities to support an ELISA based Histone PTM multiplex service, expansion of its content and sample type (25%). This includes:

• Develop protocols and screen top candidate antibodies for specificity and evaluate performance in value-added applications including, but not limited to immunofluorescent staining, CHIP-qPCR, Western blotting, and ELISA.
• Execute all phases of the Histone PTM multiplex assay workflow according to established protocols and draft assay reports.
• Development of new content and sample preparation methodologies for the Histone PTM service
• Execute on experimental protocols with excellence and accuracy.

Responsibilities/Duties/Functions/Tasks

• Evaluate antibody specificity and function in standard applications according to established protocols.
• Perform antibody purifications using protein A or immunogen chromatography.
• Prepare protein lysates from a variety of sample types and perform bead-based ELlSAs
• Generate antibody-bead conjugates according to project plan milestones to maintain and expand the multiplex portfolio.
• Ability to design and execute well-controlled experiments. Make detailed observations, analyze data, and interpret results. Suggest additional experiments based on research findings.
• Accurately and completely record experimental data.
• Contribute ideas and suggestions to improve standard laboratory and manufacturing techniques, improve protocols, processes and equipment.
• Read literature directly associated with assigned project.
• Works under some supervision and reports to R&D Manager
• Other duties as required and/or assigned.

• Bachelor degree and a minimum of three years laboratory experience or Master degree and one year post-graduate laboratory experience. Degree must be in Biology, Biochemistry or other related discipline or equivalent knowledge.
• Demonstrated proficiency in antibody based techniques including ELISA, western blotting or antibody purification.
• Working knowledge of experimental design and demonstrated time management skills.
• Demonstrated proficiency in the use of basic laboratory techniques, equipment and materials required.
• Proficiency using Microsoft Word, Excel, Powerpoint

Special Position Requirements

• Occasional domestic and international travel may be required

• Medical Insurance (m/d/v)
• Life Insurance

• 401(k)

• 10 days of PTO
• 11 paid holidays
• Working with a team that is driven by collaboration and communication!