- Carlsbad, CA, USA
- Full Time
|
Who Are We? |
Active Motif, Inc. is a privately held biotechnology company focused on supplying innovative kits and reagents for epigenetics and nuclear function research.
What Do We Value? |
Commitment to Customers
Commitment to Excellence
Innovation
Accountability
Integrity
Teamwork
What's the Job all About? |
The position has dual responsibilities, split between development of new recombinant and polyclonal antibodies and their characterization in value-added applications (75%) and performing activities to support an ELISA based Histone PTM multiplex service, expansion of its content and sample type (25%). This includes:
- Develop protocols and screen top candidate antibodies for specificity and evaluate performance in value-added applications including, but not limited to immunofluorescent staining, CHIP-qPCR, Western blotting, and ELISA.
- Execute all phases of the Histone PTM multiplex assay workflow according to established protocols and draft assay reports.
- Development of new content and sample preparation methodologies for the Histone PTM service
- Execute on experimental protocols with excellence and accuracy.
Responsibilities/Duties/Functions/Tasks
- Evaluate antibody specificity and function in standard applications according to established protocols.
- Perform antibody purifications using protein A or immunogen chromatography.
- Prepare protein lysates from a variety of sample types and perform bead-based ELlSAs
- Generate antibody-bead conjugates according to project plan milestones to maintain and expand the multiplex portfolio.
- Ability to design and execute well-controlled experiments. Make detailed observations, analyze data, and interpret results. Suggest additional experiments based on research findings.
- Accurately and completely record experimental data.
- Contribute ideas and suggestions to improve standard laboratory and manufacturing techniques, improve protocols, processes and equipment.
- Read literature directly associated with assigned project.
- Works under some supervision and reports to R&D Manager
- Other duties as required and/or assigned.
What You Can Offer! |
- Bachelor degree and a minimum of three years laboratory experience or Master degree and one year post-graduate laboratory experience. Degree must be in Biology, Biochemistry or other related discipline or equivalent knowledge.
- Demonstrated proficiency in antibody based techniques including ELISA, western blotting or antibody purification.
- Working knowledge of experimental design and demonstrated time management skills.
- Demonstrated proficiency in the use of basic laboratory techniques, equipment and materials required.
- Proficiency using Microsoft Word, Excel, Powerpoint
Special Position Requirements
- Occasional domestic and international travel may be required
What We Offer You! |
- Medical Insurance (m/d/v)
- Life Insurance
- 401(k)
- 10 days of PTO
- 11 paid holidays
- Working with a team that is driven by collaboration and communication!
